Preclinical study of a novel therapeutic vaccine for recurrent respiratory papillomatosis
نویسندگان
چکیده
منابع مشابه
Therapy for recurrent respiratory papillomatosis.
Human papillomaviruses types 6 or 11 are aetiological agents of recurrent respiratory papillomatosis, a disease characterized by benign exophytic tumours usually on the vocal cords. Surgery debulks the tumours, but these growths generally recur at regular intervals. Adjunct medical treatments, aimed at containing the virus and growth of tumours, include indole-3-carbinol or its dimer diindolylm...
متن کاملRecurrent respiratory papillomatosis: a review.
Recurrent respiratory papillomatosis (RRP), which is caused by human papillomavirus types 6 and 11, is the most common benign neoplasm of the larynx among children and the second most frequent cause of childhood hoarseness. After changes in voice, stridor is the second most common symptom, first inspiratory and then biphasic. Less common presenting symptoms include chronic cough, recurrent pneu...
متن کاملEpidemiology of recurrent respiratory papillomatosis.
Recurrent respiratory papillomatosis (RRP) was first described in the 1800s, but it was not until the 1980s when it was convincingly attributed to human papilloma virus (HPV). RRP is categorized into juvenile onset and adult onset depending on presentation before or after the age of 12 years, respectively. The prevalence of this disease is likely variable depending on the age of presentation, c...
متن کاملTherapeutic approaches to the treatment of recurrent respiratory papillomatosis of the aerodigestive tract (a clinical study)
Recurrent respiratory papillomatosis (RRP) is a rare disease, characterized by recurrent proliferation of benign squamous cell papillomas in the larynx as well as in the other parts of the aerodigestive tract. We have compared different treatment options for RRP of the aerodigestive tract including surgical, conservative and combined approaches. A total of 43 patients with papillomatosis that r...
متن کاملAdjuvant antiviral therapy for recurrent respiratory papillomatosis.
BACKGROUND This is an update of a Cochrane Review originally published in Issue 4, 2005 of The Cochrane Library.Recurrent respiratory papillomatosis is a condition characterised by benign papillomatous (wart-like) growths in the upper airway. It can affect both adults and children causing airway obstruction and voice change. Treatment usually involves repeated surgical debulking of the papillom...
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ژورنال
عنوان ژورنال: npj Vaccines
سال: 2021
ISSN: 2059-0105
DOI: 10.1038/s41541-021-00348-x